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BALTIMORE -- Even though the Boston Red Sox insist that theyve turned the page from last year, their first win of the season was eerily reminiscent of 2013. Black Friday Yeezy . David Ortiz and Mike Napoli homered, John Lackey threw six sharp innings and Boston ruined the Baltimore debut of Ubaldo Jimenez with a 6-2 victory Wednesday night. Dustin Pedroia had four hits for the defending World Series champion Red Sox, now 1-1 after losing to Baltimore on opening day. "Dustin, David and Mike. Thats three of the better hitters in the league," said Boston manager John Farrell, who rode the trio to 97 wins during the 2013 regular season. Lackey (1-0) looked even sharper than he did last year, when he had a 3.52 ERA in 29 starts. In this one, the right-hander allowed two runs and three hits before handing the ball to the bullpen, which finished with three scoreless innings. "I just threw country hard balls the first few innings, then was able to mix in other pitches later on," Lackey said. "I was very pleased for the first time. It felt pretty good. Its something I can keep building on." Lackey said he made "one mistake" -- an 0-2 pitch that Nelson Cruz hit over the right field wall for his second homer in two games. But the Orioles did little else right against Lackey, who walked one and struck out six in improving to 14-5 lifetime against Baltimore. "He had command and he was throwing strikes and he was working fast," Orioles catcher Matt Wieters said. "It seemed like it was the fourth or fifth inning before we really started to see some pitches over the middle of the plate. Youve got to tip your hat to him. When he can locate like that with his kind of stuff, youre going to have success." Ortiz connected in the third inning and Napoli made it 4-2 with a two-run shot in the fifth. Both homers came off Jimenez (0-1), who signed a four-year contract with the Orioles in February after winning 13 games with Cleveland last year. "The one to David, that was a good pitch," Jimenez said. "It seems like he was looking for that pitch and he hit it good. But the one to Napoli, I would definitely like to have that back. Oh-and-2, big mistake. I was trying to go away and left it right down the middle." Jimenez allowed four runs, five hits and three walks in six innings. He struck out six in his lamentable Orioles debut. "You always want to win. But it is part of the game," he said. "Thats how it goes. I still have 30 more games to go. I have to get ready for my next one." Ortiz put the Red Sox up 2-0 in the third inning with a drive to right following a single by Pedroia. Ortiz was 0 for 7 lifetime against Jimenez before connecting. "The pitch to Ortiz wasnt a bad pitch," Wieters said. "He was probably looking for something in and he got it and he didnt miss it. Youve got to give him credit." Lackey gave up a leadoff single to Nick Markakis, then retired 11 straight before Chris Davis walked with two outs in the fourth. Cruz followed with an opposite-field drive to right on an 0-2 pitch. Signed as a free agent in February, Cruz has accounted for all of Baltimores four runs this season -- three RBIs and a run scored. In the fifth, Jimenez hit Daniel Nava with a pitch and Napoli homered on an 0-2 count. Boston pulled away in the seventh against Ryan Webb. After two singles and an intentional walk to Ortiz loaded the bases, Napoli lined a two-run single to left. Napoli had a major league-leading 31 RBIs last year with the bases loaded. And this year, nothings changed. "In that situation, youve got one out and the bases loaded, so Im just trying to hit a flyball to get the run in," Napoli said. "I just happened to get a base hit, so thats extra. Its nice to come through in those situations." NOTES: Thursday nights series finale features a duel of left-handers: Bostons Felix Doubront against Wei-Yin Chen. ... Baltimore LHP Johan Santana, seeking to rebound from shoulder surgery, threw 30 pitches off a full mound Wednesday in Florida. "Its encouraging to see that Johans throwing all his pitches," manager Buck Showalter said. ... David Lough went 0 for 4 and Steve Lombardozzi went 1 for 3 in their Orioles debut. ... Lackey has gone at least five innings in 23 of 24 starts against Baltimore. Clearance Yeezy . About seven hours before facing Washington in Game 2 of the Eastern Conference second round series, team officials said the oft-injured Bynum would miss the rest of the playoffs and would not even be with the team for the rest of the post-season. Yeezy Outlet . Reyes, 26, was traded from Atlanta to Toronto in July 2010 and spent the remainder of the season in the minors. He began 2011 in the majors and made 20 starts with the Blue Jays, going 5-8 with a 5.40 earned run average before he was waived on Aug. https://www.fakeyeezywholesaleonline.com/ . After a 99-97 loss to the Toronto Raptors on Wednesday night, his Celtics coaches and teammates have only positive things to say about the Toronto-born rookie.ORCHARD PARK, N.Y. -- The Buffalo Bills monthlong shuffle at quarterback is coming to an end after rookie starter EJ Manuel returned to practice Wednesday. Manuels presence on the field, and the expectation that hell be ready to step in immediately and start against the Pittsburgh Steelers (2-6) on Sunday, has provided the Bills a much-needed lift. "Yeah, were excited to get EJ back," centre Eric Wood said. "Hopefully, it gives us a boost, offensively." And dont underestimate the importance of Manuel re-establishing stability at a position that was mostly unsettled in the four weeks since the first-round draft pick out of Florida State sprained his right knee. "Hes the guy that we wanted to be back there, and weve got him back there now," running back Fred Jackson said. "To get some stability there, a guy thats going to be there for the remainder of the season hopefully is something that can help this offence move in the right direction." The Bills (3-6) were going nowhere in losing three of four without Manuel, who was hurt in a 37-24 loss at Cleveland on Oct. 3. The injury prompted a scramble by the team to find a capable replacement at a position where Buffalo lacked experienced depth. Journeyman Thad Lewis was promoted from the practice squad to take over as interim starter after undrafted rookie Jeff Tuel struggled filling in for Manuel against the Browns. Lewis went 1-2 before he was sidelined by bruised ribs, which led to Tuel making his first career start in a 23-13 loss to the Kansas City Chiefs last weekend. Tuels inexperience was once again evident against the Chiefs. He threw two interceptions, the second one returned 100 yards for a touchdown in a game where Buffalo squandered a 10-3 halftime lead and outgained Kansas City 470-210. Manuel was cleared to play earlier this week after spending most of last week working out individually. On Wednesday, Manuel showed no signs of a limp while dropping back to passs, and he completed several throws into gusty winds during a 20-minute portion of practice open to the media. Yeezy Sale. "Yeah, very confident. Pushing off it fine. Running around and making plays," Manuel said. "Its still up to coach as far as what we want to do as a team, but I definitely feel confident going into Sunday." Coach Doug Marrone liked what he saw, and acknowledged that Manuel is expected to start barring any setbacks. "From a standpoint of being healthy, hes fine," Marrone said. "Now its just to the point of really trying to get him back." Plan B would be starting Lewis, who also returned to practice Wednesday. Manuel might not have all that much more experience than Lewis or Tuel. But he has had the most time in learning Marrones offence, and showed a capability of running it in going 2-2 before he was hurt. In four-plus games, Manuel went 85 of 150 for 985 yards passing with five touchdowns with three interceptions and a lost fumble. Lewis and Tuel combined to produce similar numbers in going 88 of 162 for 961 yards and four touchdowns. They struggled in protecting the ball by committing eight giveaways: five interceptions, including two returned for touchdowns; and three lost fumbles. At 6-foot-4 and 240 pounds, Manuel has a strong arm and provides an element of mobility to the Bills up-tempo attack. The only issue with him is avoiding hits, as happened against Cleveland when he elected to keep running rather than get out of bounds before being struck in the right knee by safety Tashaun Gipson. Manuel also missed the final two preseason games with a left knee injury. Manuel is defensive when it comes to answering questions about his running style. He went so far as to describe his latest injury as "a freak accident." "If I lifted my knee up a half-inch more it wouldnt have been a problem," he said. Manuel added it hasnt been yet determined whether hell play with a protective brace. ' ' '